The incidence of cervical cancer in young women appears to be increasing. However, the influence of young age on prognosis remains unknown.
There is almost no information on the prognosis of young women, age 35 years or less, with invasive cervical carcinoma. From Jan. 1980 to Dec. 1993, the clinical courses of 65 patients with 35 years orless were reviewed and compared with that of
579
patients with 36 years or more.
@ES We obtained the following results:
@EN 1. There was an increasing tendency of patients with 35 years or less during 2 year time interval between Jan. 1980 to Dec. 1989, but a decreasing tendency was showed after Jan. 1990
2. The lower the patient's age, the higher the incidence of clinical stage I. and the higher the patient's age, the higher the incidence of clinical stage II, III, IV(p<0.05).
3. the 156-months disease rree survival rate for patients with 35 years or less was 83.2% versus 60.0% for matched patients with 36 years or more in all stages. This difference was not statistically significant(P>0.05).
4. The 150-months disease free survival rate for patients with 35 years or less was 86.1% versus 80.0% for matched patients with 36 years or more in stage I. This difference was not statistically significant(P>0.05).
5. The 90-months disease free survival rate for patients with 35 years or less was 60.0% versus 70.0% for matched patients with 36 years or more in stage II. This difference was statically significant(P<0.05).
6. The 70-months disease free survival rate for patients with lymph node metastasis was 83.3% versus 84.2% for matched patients without lymph node metastasis in patients with 35 years or less. This difference was not statistically significant
(P>0.05).
7. The 144-months disease free survival rate fur patients with tumor size above 4.0 cm was 82.3% versus 90.9% for matched patients with tumor size below 4.0 cm. This difference was not statistically significant(p>0.05).
In most stages of disease their clinical characteristics was similar to that of older patients, and in stage II their prognosis was considerably worse. But it is not possible to evaluate the question statistically from this group of cases, and it
must
remain an individual problem for each patient under consideration. This time honored percepts of early diagnosis, adequate treatment, and careful post-treatment follow-up are nowhere more mecessary than in the younger age group.
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